The southern half of the Regency comprises the large but landlocked and nearly uninhabited Naikere District.

[4] Most of the islands in Wondama Bay Regency are surrounded by coral reef that is teeming with rich marine life.

Rasiei, the administrative capital of Wondama Bay, is a small port located on the east coast of Wondama Bay at the foot of the Wandammen or Wondiboy Peninsula which is covered by pristine tropical rainforest.

Most of the Wandamen or Wondiwoi Peninsula is covered by the Wondiwoi Mountains (Pegunungan Wondiwoi) National Reserve, while most of the islands in the north of the regency (together with Anggrameos Island which lies off the east coast of the Peninsula and is part of Central Papua Province) are included in the Cenderawasih Bay National Park (formerly described as a Marine Nature Reserve until re-designated in 2002).

Roon District comprises seven villages, all on Roon Island (there are no villages on the smaller islands within the district) - Menarbu (which had 208 inhabitants at the 2020 Census), Sariay (with 14 inhabitants), Niab (227), Inday (235), Syabes (509), Mena (228) and Yende (414).