The museum occupies part of a reconstructed fortification,[4] originally built by Karl Friedrich Emil zu Dohna-Schlobitten in the Napoleonic wars.

The amber museum was established in Kaliningrad because near the town of Yantarnoye there is the largest (out of the discovered) deposit of the Baltic gem - more than 90% of the world's reserves.

The museum is the only owner of fragments of the decor of the Amber Room, restored by artists G. Khozatsky, V. Ertsev, V. Vorobyov, A. Zhuravlev, A. Vanin, M. Ertseva and L. Grigorieva.

Amber products of the 4th-5th centuries AD, also found by archaeologists on the territory of the Kaliningrad region, were exhibited, as well as works by German masters handed over from the Armory Chamber.

[10] Among the partner countries are Latvia, Lithuania, Poland, Germany, Sweden, Denmark, Japan, United States, Italy, Austria, France.

In total for the period of 2004-2008 about 100 exhibitions were held, the collection of the museum was replenished with 10 000 items of storage, including antiquarian objects, works of foreign artists and unique inclusions.