She also married her brother-in-law, chief Keōua, and had a daughter Kekuiapoiwa Liliha.
Kekuiapoiwa Liliha married Kīwalaʻō and their child was Queen Keōpūolani, consort of Kamehameha I and mother of two kings.
[5][3] She was also married to her brother Kamehamehanui Aiʻluau at one time with whom she was the mother of Kalanikauikikilokalaniakua, the highest ranking chiefess in her days on whom the sun was not permitted to shine and who was allowed to climb about the kapu heiau of the kapu gods.
Kalanikauikikilo committed suicide in 1808 at Honuakaha by taking the kālaipāhoa poison in protest of the marriage of her niece to Kamehameha I.
[6][4] Kalola was married to a chief by the name of Kaopuiki at the time the American ship Eleanora was in Maui in 1790.