Starting after the events of the original series, Shiro Kazami witnesses a murder by Destron, a new organization created from Gel-Shocker by its previously thought deceased leader.

Destron is the only Showa villainous organization in the franchise to appear in the movie OOO, Den-O, All Riders: Let's Go Kamen Riders although several of its monsters make appearances; this is most likely due to the organization being formed from Shocker remnants, therefore making its construction unnecessary.

A physicist named Tetsuo Okita discovers a new mineral called "satanum",[14] which is more powerful than uranium and emits destructive effects to anyone exposed to it.

However, Destron abducts Okita in hopes of finding the source of satanum and collecting more of it to expedite their run for global domination.

Kamen Rider V3 must act fast in rescuing Professor Okita and preventing Destron from collecting more of the deadly mineral.

[16] • In 2008, the Hawaii-based company JN Productions/Generation Kikaida released Kamen Rider V3 on a remastered six-disc complete series Region 1 DVD set in Japanese with English Subtitles.

[17] • In 2024, Discotek Media announced that they had licensed Kamen Rider V3 with plans to release the full 52 episode series on Blu-Ray later that year remastered in HD, along with a brand new English-subtitle translation and many extras included on the set.