Kamezaki Station (亀崎駅, Kamezaki-eki) is a railway station on the Taketoyo Line in the city of Handa, Aichi Prefecture, Japan, operated by Central Japan Railway Company (JR Central).

The JGR became the Japan National Railway (JNR) after World War II.

With the privatization and dissolution of the JNR on April 1, 1987, the station came under the control of the Central Japan Railway Company.

Automatic turnstiles were installed in May 1992, and the TOICA system of magnetic fare cards was implemented in November 2006.

The station building, dating from 1886 and rebuilt after a fire in 1895, is one of the oldest in Japan.