The hospital is administered and regulated by the Kanti Children's Hospital Development Board, an autonomous body under the Ministry of Health, Government of Nepal.

There are 36 pediatricians, 8 pediatric surgeons, 45 medical officers, 84 general nurses, 25 technicians and paramedics and 107 support staff.

The hospital also runs a Post Graduate Degree class with accreditation from National Academy of Medical Education and Sciences (NAMS), Nepal.

In 1968 Kanti Hospital was handed over to the Ministry of Health of Nepal by the USSR government.

[2] From 1970 the hospital started providing its services for treatment of children up to the age of 14.