The Kara Musa Pasha Mosque (Greek: Τζαμί Καρά Μουσά Πασά, Turkish: Kara Musa Paşa Camii) is a historical Ottoman mosque in the town of Rethymno, on the island of Crete, Greece.

Located on Arkadiou street, it was most likely erected during the 1680s, or right after the conquest of the city in 1646,[1] perhaps by the Ottoman governor of Crete,[2] on the site of a Venetian monastery dedicated to Saint Barbara.

[2] It has been restored by the Greek Archaeological Service, and is being considered to be made into a museum about the Ottoman architecture of Crete.

[2] After the monastery's conversion into mosque in the seventeenth century, a dome and a minaret was added to it by the Ottoman Turks.

A turbes (a type of vaulted funerary structure) is preserved in the precinct, in which the founder of the mosque, Kara Musa Pasha, was probably buried.