The Karakoro River (French: Rivière Karakoro) is a small seasonal tributary of the Sénégal River that forms part of the Mauritania-Mali border.
The source of the river is northeast of Kiffa in Mauritania.
The river flows south in the flat sahel region of southern Mauritania, crossing a number of shallow depressions, before joining the Sénégal River on the left bank a few kilometres downstream of the small Malian town of Ambidedi.
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