[citation needed] Christman was a doctoral researcher at the University of California, San Francisco (USCF), where she developed in situ approaches for myocardial tissue engineering.

[4] After her PhD, she moved to the University of California, Los Angeles for postdoctoral research, working with Heather Maynard on polymer chemistry to develop new strategies for site-specific patterning of proteins.

[4] In particular, Christman has studied myocardial infarction, which is a leading cause of death worldwide and from which many people do not recover full function.

[4] In 2017, Christman was one of the most highly funded researchers at UCSF, receiving a large grant from the California Institute for Regenerative Medicine to study peripheral artery disease.

[6] She is the founder of Ventrix, Inc,[7][8] which looks to create a new class of biotherapeutics that help the extracellular matrix guide the body to generate healthy tissue.