[1] He worked and carried out research at the Matenadaran in Yerevan beginning in 1955 until he transferred to the Leningrad branch of the Institute of Oriental Studies in 1958.
[2] In 1974, he received his doktor nauk after completing his thesis on the work of the eleventh-century Armenian historian Aristakes Lastivertsi.
Just prior to the Soviet Union's collapse, Yuzbashyan was elected into the Armenian parliament, serving a five-year term (1990–1995) there.
He taught at St Petersburg State University and was the doctoral adviser of many students who entered the field of Byzantine Studies.
In addition to works on medieval Armenian history, Yuzbashyan also completed a biography of his academic mentor, Joseph Orbeli, in 1964.