He composed, among other pieces, a cantata mourning of the death of Moses Mendelssohn, (Sulamith und Eusebia , 1786).
After the prince's death in 1802 he largely gave up his musical career and became a low-ranking civil servant in Berlin and later in Potsdam, where he founded a club for classical music, which he headed until his death.
He was a member of the Berlin Freemason's Lodge "Friedrich Wilhelm zur gekrönten Gerechtigkeit".
[2] Wessely composed several operas, ballet and incidental music for the theatre, Lieder, funeral cantatas and string quartets.
He was also active as a musicological writer and supplied journal articles, especially for the Archiv der Zeit and the Allgemeine musikalische Zeitung.