[3] In summer 2017 Karl Strauss was declared the Mid-Size Brewery of the Year at the Great American Beer Festival.

[4] Strauss agreed, contributing his library of hundreds of beer recipes, helping to design brewing operations, and serving as the company's spokesman on radio advertisements and in public appearances until his death in 2006.

In 1996 the company's distributing brewery operations were moved into a 22,000-square-foot (2,000 m2) home office and brewing building in Pacific Beach.

Additional brewpubs were opened in La Jolla (1996) (location closed as of January, 2021), Carlsbad (1999), Costa Mesa (2002), 4S Ranch in San Diego's North County (2012), Temecula (2013), Anaheim (2016) and downtown Los Angeles (2016).

[9] In 2023 a new Karl Strauss beer location opened called Port of San Fransokyo Cervecería at the Disney California Adventure theme park in Anaheim.