Otto Karl Wiesenburg (August 1, 1911 – June 18, 1990) was an American legislator, lawyer, and public servant.
He attended Public School 74 and was later admitted to Townsend Harris Hall, before dropping out at the age of 16, following the death of his father, to support his mother.
Although he had met his military obligation with five year's service in the Coast Guard, Wiesenburg joined the United States Army on May 2, 1942 and served overseas for 42 months during World War II as a radio operator in India, Burma, and China, rising to the rank of captain.
Devoted to public service, Wiesenburg was appointed to the Pascagoula Port Commission in 1941 and served as its president.
During the period when James Meredith entered the University of Mississippi as its first black student, over the opposition of Governor Ross Barnett and the Mississippi Legislature, Wiesenburg was one of two legislators, the other being Joe Wroten of Greenville, who took a strong stand for civil rights and observance of the law.
His family has established the Karl Wiesenburg Scholarship at the University of Southern Mississippi to honor his commitment to education and public service.
Wiesenburg died on June 18, 1990, from cardiac arrest, at Singing River Hospital in Pascagoula.