Karluk (Kal’uq or Kal’ut[3] in Alutiiq; Russian: Карлук) is a census-designated place (CDP) in Kodiak Borough, Kodiak Island, Alaska, United States.

Karluk first appeared on the 1880 U.S. Census as an unincorporated village with 302 residents, including an Inuit majority of 277, with 24 "Creole" (Mixed Russian & Native) and 1 White.

In 1890, it reported 1,123 residents, making it the 3rd largest community in Alaska, narrowly behind Juneau with 1,253 and the then-capital of Sitka with 1,190.

In 1787 Evstratii Delarov, manager of the Russian Shelikhov-Golikov Company established an outpost at Karluk.

[9] On March 17, 1945, the village participated in the rescue of seven (7) U.S. Navy aviators who ditched their PB1 Ventura patrol bomber offshore.

[10] In 2021, the Ascension of Our Lord Chapel was relocated from a bluff overlooking the river to prevent its destruction.