[1] The character Karnak Mander-Azur[2] was never exposed to the Terrigen Mists, so he never developed additional powers like other Inhumans, but he is a martial artist who can find the weakness in anything and then use his training and strength to exploit it.

Although the Jack Kirby Collector described him as "a philosophical karate expert with nominal personality" in 2004,[3] subsequent writers have made use of his skill for puzzle-solving[4] and strategic-planning[5] in Inhumans' stories, leading to him being given his first solo series in 2015, titled Karnak: The Flaw in All Things and written by Warren Ellis.

[6] Karnak made his live-action debut in the 2017 Marvel Cinematic Universe (MCU) television series Inhumans, portrayed by Ken Leung.

Karnak first appeared in Fantastic Four #45, and was created by Stan Lee and Jack Kirby, as part of their run on the title that helped lay the foundations for the Marvel Universe.

Karnak is the narrator of Inhumanity #1 (February 2014)[7] because his abilities gave writer Matt Fraction a way to frame the story: I needed somebody who could put puzzles together.

His power is the ability to see weakness and stress points in anything around him, which he then exploits either physically through his amazing kung fu-esque fighting skills, or mentally/strategically in his role as one of Queen Medusa's chief counselors.

He tends to have a fascinating perspective on events, and adding his voice back into the mix of the "Inhuman" cast will open up some great new possibilities.

[10] Editor-in-Chief Axel Alonso has said that the specific series came about because "Nick Lowe was looking to build the Inhumans line with a solo book or two and suggested Karnak as a character to spotlight.

His parents refused to allow him to become an Inhuman, and instead he studied at the Tower of Wisdom until his natural powers of perception became so phenomenally strong that he could annihilate anything by touching it.

In this new Marvel Universe situation, where all kinds of people have been mutated by Terrigen, there’s an endless number of plot launches there.

Cousin of Black Bolt, king of the Inhumans, Karnak has the ability to find the weak point in any person, plan, or object.

Karnak and the Royal Family encounter Maximus' creation, the Trikon, and are driven from Attilan's Great Refuge in exile.

[14] Karnak first appeared as a member of the Inhumans when he attempted to retrieve his cousin and queen, Medusa from the outside world and take her back to Attilan.

[15] He was freed from the "negative zone" barrier along with the rest of the Inhumans by the Fantastic Four and left the Great Refuge with the Royal Family to visit the outside world.

Later they became entangled in Mephisto's plot against Daredevil, and were transported to a netherworld where they were personally attacked by the supernatural entity known as Blackheart.

After warning Medusa to forget what she knows to prepare for a coming cataclysm, Karnak commits suicide by leaping out of one of the windows in Avengers Tower.

[40] During the Civil War II storyline, Karnak was at New Attilan when Iron Man infiltrated it to claim Ulysses.

Karnak was present when Ulysses projected his latest vision that involved a rampaging Hulk standing over the corpses of the superheroes.

[44] Karnak has enhanced strength, stamina, durability, agility, and reflexes as a result of his genetically superior Inhuman physiology.

Instead, Karnak has the extrasensory ability (achieved through meditation and intensive training) to perceive stress points, fracture planes, or weaknesses in objects or persons.

He is capable of shattering substances up to and including mild steel and rendering superhuman opponents unconscious by striking them.

[volume & issue needed] An alternate universe variant of Karnak from Earth-42777 who was infected by the Phalanx appears in Exiles.

[46] An alternate variant of Karnak from a pocket dimension created by Franklin Richards appears in Heroes Reborn.