Karomama II (full name Karomama Meritmut; also known as Karomama D, Merytmut II)[1] was an ancient Egyptian queen, Great Royal Wife of pharaoh Takelot II of the 23rd Dynasty of Egypt.

She was a daughter of the High Priest of Amun Nimlot C and the lady Tentsepeh C. Her paternal grandparents were pharaoh Osorkon II and queen Djedmutesankh.

[1] Karomama also was the grandmother of both pharaohs Takelot III and Rudamun and of the God's Wife of Amun Shepenupet I[2] Karomama is known from the Chronicle of Osorkon B at Karnak and the Nile Quay Texts dating to the reign of her son Osorkon III.

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