Karthik and Anitha are childhood friends and even study at the same college, moreover, their fathers Ramachandramoorthy and Krishnamoorthy are like brothers.
Thereafter, Anitha's wedding is fixed with the wealthy engineer Gowri Shankar and Ramachandramoorthy was the one who made both families agree.
Anitha's family asks Karthik, who was consumed and distressed by the death of his father, to move in with them for a few days.
The film, produced under the banner of King Magic, had a totally urban setting and is tagged 'a neighbourhood love-story'.
[6] Sify said, "there is nothing new in the age-old squabbling friends turning lovers plot [...] Karthik Anitha is a refreshingly narrated love story.
With no lewd dialogues, item songs or vulgarity it makes for a good, clean film for family viewing".
[9] Behindwoods.com rated the film 0.5 out of 5 and wrote, "Kaartic Anithaa is a rerun of an often repeated theme of love that is unexpressed.