Karuthapillaiyur is a village in the district of Tenkasi near Ambasamudram, Tamil Nadu, India.

The name Karuthapillayur is an evolution from the mixing of three words "Karthar" "Pillai" "oor".

Karuthapillaiyur is located on the bank of Kadananathi River (Kadana Nadi).

The area is surrounded by mountains and hills which are part of the Western Ghats.

The nearest railway station is in Kizha Ambur, 5 km from the village.