The Kashgar–Hotan railway or Kahe railway (Chinese: 喀什至和田铁路; pinyin: Kāshí zhì Hétián Tiělù, abbreviated Chinese: 喀和铁路; pinyin: Kā-Hé Tiělù), is a single-track, non-electrified, railway in Xinjiang, China between Kashgar and Hotan.

The railway is 488.27 km (303.40 mi) in length and runs along the southern edge of the Taklamakan Desert, connecting all major cities and towns of the Southwestern Tarim Basin, including Shule, Akto, Yengisar, Yarkant (Shache), Poskam (Zepu), Karghilik (Yecheng), Pishan (Guma) and Karakax (Moyu).

[1] The line extends the Southern Xinjiang Railway south from Kashgar.

[1] The line opened to freight traffic on December 30, 2010.

If built, the proposed Khunjerab Railway, a part of the China–Pakistan Economic Corridor, would link Islamabad in Pakistan to Hotan and the Chinese railway network.