In this role, she was the senior author on a literature review of 31 peer-reviewed and published studies conducted in six countries on alcohol consumption, disorders, and mortality.
[4] She also reviewed 31 international studies of birth-cohort and gender differences in alcohol consumption and mortality to conclude that "those born between 1978 and 1983 are the weekend warriors, drinking to black out.
"[5] As an assistant professor of epidemiology, Keyes was the recipient of a 2015–2016 Calderone Junior Faculty Award to fund "innovative data input methods to create synthetic survey-nonrespondent observations, leading to more accurate national estimates of alcohol and tobacco use across several population subgroups.
The findings, which were based on data from a 2001–2002 United States population-representative sample of 22,581 working adults ages 30–65, found that American woman were diagnosed with depression at a higher rate than men.
[11] During the COVID-19 pandemic, Keyes was the senior author on a study which refuted claims that adolescents' heavy use of social media increased the risk of depression.