Initially available with a 454 cc (27.70 cu in) twin-cylinder engine in the original MULE 1000 model, the range has grown and been gradually updated over the years, and now includes both petrol and diesel variants.

[1] The MULE 2010 was introduced in 1989, and featured a larger 535 cc (32.65 cu in) engine, a high/low CVT transmission, selectable four-wheel-drive and a De Dion rear suspension.

[1] The MULE 2500 series was introduced in 1992 and featured a new 617 cc (37.65 cu in) V-twin engine with a fan cooled CVT.

[1] The first diesel MULE with a 953 cc (58.2 cu in) three-cylinder engine was introduced in 1999 as part of the 2500 series.

[3] In 2014, the new MULE PRO-FXT was introduced, featuring a fuel-injected 812 cc (49.55 cu in) straight-three engine, a CVT transmission, and a cab that could seat up to six people.