[1][2] The formation of starting 1949 by Dr. Mavis P. Kelsey with the purpose of combining primary and specialty medical services in one location in the city of Houston.

In 1949, Dr. Kelsey, an internal medicine specialist, leased space in the Hermann Professional Building and set up his practice.

On December 15, 1956, the Kelsey and Leary Foundation for the Advancement of Medicine was established to provide scholarships and financial support for research.

The Kelsey Foundation, as it is known today, is involved in a variety of research projects with universities, pharmaceutical companies, government bodies and hospitals in the Texas Medical Center.

The rapidly expanding Radiology Department added lab technicians, while the multi-specialty team continued to grow with the addition of a pediatrician and otolaryngologist (Ear, Nose & Throat specialist).

Dr. Stanton P. Fischer, a pulmonologist, joined the staff a year earlier and assisted in providing executive physical examinations on NASA employees and other contractors.

Concerning the ISS, Kelsey-Seybold has provided a NASA Support Physician in Moscow since the inception of the International Space Station.

In 1971, KSC opened its first neighborhood health center on Post Oak in the Uptown District of Houston.

The success of that health center resulted in other locations being operated in downtown Houston, Sugar Land, The Woodlands and by Intercontinental Airport.

Today, Kelsey-Seybold Clinic operates more than 35 neighborhood health centers in the Greater Houston area.

At the time many employees of the central office lived in communities such as the Texas Medical Center area, Fort Bend County, and Clear Lake.