[1] His television credits have included guest spots on Frasier, ER, Las Vegas, Without a Trace, Studio 60 on the Sunset Strip, CSI: NY, and Bones.
Yu later appeared with Linda Park on the ABC series Women's Murder Club, and a lead role in the 2007 short film Fortune Hunters.
Yu had a recurring role in the Netflix original series Master of None as the character of Brian Chang, the on-screen analogue of the show's creator Alan Yang, described as a "hottie" by Vulture magazine.
In 2016, he won an Annie Award for Outstanding Achievement in Writing in an Animated TV/Broadcast Production (along with co-writer Steven Davis) for the episode "The Hauntening.
In October 2021, it was announced that Disney+ had given a series order to a television adaptation of the graphic novel American Born Chinese.