On the northeastern edge of the college, it intersects the northern terminus of KY 2290 (Young Street).
The two highways travel to the north-northeast and cross over Drye Branch just before intersecting the southern terminus of KY 2289 (Dunnville Road) south-southwest of Eunice.
KY 206 crosses over the Bear and Barnett creeks before curving to the east-southeast and traveling through Pellyton.
The highway then intersects the southern terminus of KY 2970 (Sanders Ridge Road) and crosses over Spruce Pine Creek before entering Casey County.
It curves to the northeast and intersects the western terminus of KY 3272 (Riffe Creek Road).