KY 2158 starts at a junction with U.S. Route 231 (US 231), known locally as Scottsville Road.

0.6 miles (0.97 km) north of this intersection, KY 2158 has a junction with KY 2629, a west–east route that begins at this point.

KY 2158 then continues north for another three miles (4.8 km) before reaching its terminus at KY 234, just east of the exit 26 interchange with I-65.

North of the intersection, the highway is primarily surrounded by residential development.

The entire route is in Bowling Green, Warren County.