The highway runs 0.970 miles (1.561 km) from U.S. Route 31W, US 68, and KY 80 east to Interstate 65 (I-65).

KY 446 is a four-lane divided highway that serves as a connector between the Interstate and U.S.

KY 446 begins at a modified trumpet interchange with Louisville Road, on which US 31W, US 68, and KY 80 run concurrently, at the eastern edge of the city of Bowling Green.

The Kentucky Transportation Cabinet classifies KY 446 as a state primary highway.

[1][2] The entire route is in Bowling Green, Warren County.