Kentucky Route 480 (KY 480) is a 13.481-mile-long (21.696 km) state highway in Kentucky that runs from Kentucky Route 61 in southern Shepherdsville to Kentucky Route 523 in rural Nelson County southeast of Mt.

Washington via Cedar Grove.

Kentucky Route 480C (KY 480C) is a 0.916-mile-long (1.474 km) state highway in Shepherdsville, Bullitt County, Kentucky that serves as a connector route for Kentucky Route 480.

It runs from Kentucky Route 61 to Kentucky Route 480 in southern Shepherdsville.

The entire route is in Shepherdsville, Bullitt County.