Blankenbaker Parkway originates at a junction with KY 155 in a residential area east of Jeffersontown.

Blankenbaker Parkway then curves back toward the north and passes through an industrial area.

After forming a junction with Plantside Drive, Blankenbaker Parkway becomes three lanes in both directions, passing through a commercial area with many businesses, restaurants, and hotels lining the roadway.

After passing over I-64, Blankenbaker Parkway narrows to two lanes in both directions and passes by the main campus of Southeast Christian Church, one of the largest churches in the United States.

It forms a concurrency with KY 1819 at the northeast corner of the church property and carries this concurrency for 0.586 miles (0.943 km) to its northern terminus at US 60.