Keo is a town in southwest Lonoke County, Arkansas, United States.

Arkansas Highway 15 leads north from Keo 16 miles (26 km) to Furlow and southeast with US 165 to England.

The racial makeup of the town was 19.87% White, 80.33% Black or African American, 0.43% from other races.

Keo is known as one of Arkansas' largest pecan producers with a rich history in farming of cotton and rice.

As in much of the surrounding region, agriculture is the driving economic force in the area around Keo, primarily in the cultivation of cotton, rice, soybean, and fish farms.

The climate in this area is characterized by hot, humid summers and generally mild to cool winters.