Keowee Key is a lakeside community and census-designated place (CDP) in Oconee County, South Carolina, United States.

[4] The CDP is on the eastern edge of Oconee County, on a peninsula extending into Lake Keowee, a reservoir on the Keowee River and Little River.

The arm of the lake on the Little River borders the western side of the peninsula, while the Keowee River arm forms the eastern side and is the border with Pickens County.

The two arms of the lake join via a small channel in the south part of the CDP; to the south, across the channel and outside the CDP, is the Oconee Nuclear Station power plant.

This South Carolina state location article is a stub.