West Union is a town in Oconee County, South Carolina, United States.

The larger city of Walhalla borders the town to the west, and Lake Keowee lies just a few miles to the east.

According to the United States Census Bureau, the town has a total area of 0.8 square mile (2.0 km2), all land.

West Union elected Dorothy “Dot” Gibson, their first female mayor, from 2002-2004.

38.1% of all households were made up of individuals, and 15.7% had someone living alone who was 65 years of age or older.