Deposits of this mineral have been found all over the world, however notable deposits have been found in Braunsdorf, near Freiberg, Saxony, Germany; Pernek, Pezinok, and Pribram, Czechoslovakia; the Lac Nicolet mine, South Ham Township, Wolfe County, Quebec, Canada; Sombrerete, Zacatecas, Mexico; Santa Cruz and San Francisco mines, Poopo, Oruro, Bolivia; Que Que, Zimbabwe; Djebel Haminate, Algeria; Broken Hill, New South Wales, Australia; Mohave, Kern County, California and Burke, Shoshone County, Idaho.

Earlier in English (17th and 18th centuries) certain antimony compounds were called "kermes mineral" for the same reason.

[6] Kermesite or red antimony has been used as early as the Old Kingdom’s 6th Dynasty in ancient Egypt (c. 2345–2181 BCE) in lip cosmetics and in the 18th Dynasty Queen Hatshepsut (Maatkare) (1498–1483 BCE) negotiated with the Land of Punt for its colored antimony deposits.

Besides stibnite, which was used for eye liner red, antimony is one of the oldest minerals used in cosmetics.

Kermesite is the mineral state for Kermes mineral which was used extensively in the medical field for centuries Presently, kermesite is collected for the beauty of its crystal metallic structure and not used in either cosmetics or the medical field any longer due to the toxic effects that it shares with antimony; less harmful substitutes have been found using both organic and pharmaceutical production.