The Keyauwee village was surrounded by palisades and cornfields about thirty miles northeast of the Yadkin River, near present day High Point, North Carolina.

The Keyauwee would move further southward along with the Cheraw and Peedee tribes, close along the border of the two Carolinas, where they conducted deerskin trade with Charleston traders and allied with the Indian neighbors in the Yamassee War.

[3] In 1701, English explorer John Lawson, on an expedition over 1,000 miles, contacted the Keyauwee tribe, a small group which numbered about 500 people.

[7] Tribal merging in North Carolina was inhibited by relationships built on exchange and alliance, and circular rounds of war, peace, and trade.

[8] Later, the Keyauwees moved towards the Albemarle Sound region, situated on the northeastern coast of North Carolina, to form settlements with the Occaneechi and Shakori tribes.