As of 2024, Kherson State University is attended by approximately 8000 students from 23 regions of Ukraine and other CIS countries.

Kherson State conducts scientific-educational work with institutes of higher education located in Kyiv, Odessa, and the Crimea.

Its campus contains 4 educational buildings and laboratories, agricultural and biological research stations, a library, recreation zones on the Dnipro bank and on the Black Sea shore, a students' café, a students' club, a sports club, an observatory, three gymnasiums, two conference halls, and an agricultural machinery building.

In March 1944, after the release of Kherson from Axis invaders, it resumed the educational process in 6 departments: physical, mathematical, scientific, linguistic and literary, geographical, and historical.

[clarification needed] In 1994 the university opened a school of physical education and sport, and Kherson Academic Lyceum at KSU.