Kho Laen (Thai: คอแลน) is a tambon (subdistrict) located in the northeastern region of Buntharik district, in Ubon Ratchathani Province, Thailand.

[1] Neighbouring subdistricts are (clockwise from the south) Phon Ngam, Nong Sano, Ban Maet, and Non Ko, as well as the Champassack district of Laos in the east.

Due to the outbreak, the original settlers resettled 4 kilometers eastwards to a new location, Kho Laen village, on the east side of the river.

[3] A new village was named after a tropical fruit tree known as "Korlan" (Nephelium hypoleucum), which was found numerously in the area.

[3] Kho Laen was one of the three oldest subdistricts (tambon) of the Buntharik district, together with Phon Ngam and Huai Kha.