Kholodnohirskyi District (Ukrainian: Холодногірський район) is an urban district of the city of Kharkiv, Ukraine, named after a neighborhood in the city Kholodna Hora.

In 2016 it was renamed into Kholodnohirskyi to comply with decommunization laws.

The region's industry is represented by 61 enterprises, of which: More than 51% of the total volume of production is produced by enterprises of the processing and food industry.

Quite a wide range of industrial products: refrigerating and freezing equipment, heating boilers, metal cutting machines, pumps, hydraulic stations, presses, stamps and molds, engines, direct current machines, electric motors for mine electric locomotives, electric pumps, electromagnetic clutches, circuit breakers, prosthetics— orthopedic products, electric razors, electric, heat, and water meters, freight cars, plastic and film products, heat exchange equipment, secondary aluminum alloys, prefabricated concrete and reinforced concrete products; food industry: grape champagne, table and strong wines, confectionery in the assortment of Kharkiv Biscuit Factory, ice cream and chocolate wafer products of Polyus LTD JV; products of light industry enterprises: outerwear, bed linen; book and magazine production.

There are two theaters — the Musical Comedy and the Theater for Children and Youth, two cinemas, 8 centralized libraries, 9 parks and squares, clubs and houses of culture (the House of Science and Technology of Railway Workers, the garrison House of Officers with 840 seats, the House of Culture of the Novyi byt microdistrict).