Khuan Don (Thai: ควนโดน, pronounced [kʰūa̯n dōːn]) is a district (amphoe) of Satun province, southern Thailand.

The old name of Khuan Don was Duson (ดุสน), which is derived from its original Malay name, Dusun (Jawi: دوسون).

[2] Neighboring districts are (from the south clockwise) Mueang Satun, Tha Phae and Khuan Kalong of Satun Province; Sadao of Songkhla province; and the state Perlis of Malaysia.

The area near the boundary is part of the Thale Ban National Park.

The district is divided into four sub-districts (tambons), which are further subdivided into 30 villages (muban).