Khwaja Du Koh (Dari: خواجه دوکوه) is a district of Jowzjan province, Afghanistan, situated in the Karakum Desert.

It borders Faryab province to the west, Khamyab District to the north, Mingajik District to the east and Sheberghan District to the south.

The district capital is Khwaja du koh, and is located in the southern part of the district.

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