The total length of the Kifisias Avenue is about 20 km, beginning 4 km northeast of downtown Athens and ending by the municipal boundary of Nea Erythraia north of Kifisia.

The avenue passes near a forest park in Marousi, called Anavryta.

The avenue has a bus lane for a significant section of its length, close to its start.

It is a significant commercial street and office space is in considerable demand with many key Greek companies based there.

Along Kifisias Avenue, and more specifically in Psychico area many embassies and consulates are located including that of Albania,[1] Israel,[2] Cameroon, Kuwait,[3] New Zealand, South Africa, South Korean, Ukraine, Palestine, North Macedonia, Saudi Arabia, Singapore, Thailand and Tunisia.