Its route marks the boundary between the City of Westminster and the London Borough of Brent.
At the western end the street curves southwards until it meets Harrow Road, becoming Ladbroke Grove and continuing across the Grand Union Canal.
It is a historic road, marking a route from the old village of Kensal to Kilburn Priory before Henry VIII's dissolution of the monasteries in the sixteenth century.
The area was rural for most of its existence, as major development didn't take place until the nineteenth century when London expanded into new suburbs.
[2] At the junction with Harrow Road the Anglican St. John the Evangelist's Church was opened in 1844.