In June 2019, Louis Tomlinson announced his plans to release music more frequently, stating "At the moment it's three or four months in between, so I think I'm going to do two or three at once and get myself back on the road".

[3] On 29 August 2019, he posted the artwork for "Kill My Mind", writing "So happy to finally announce my new single #KillMyMind will be out a week today!

[6] Rob Copsey of the Official Charts Company wrote that Tomlinson "sounds at his most confident and comfortable yet" on "Kill My Mind", and added that there is "something very turn-of-the-noughties-indie-pop about" it.

[7] iHeartRadio's Lindsey Smith described the song as a "punk-influenced track with heavy guitars and drums", and thought that it "really showcases his talent and ability to perform different genres effortlessly".

[8] Jason Lipshutz of Billboard described the track as "the song that lets a pop star rock out" and called it "brash, swaggering and catchy as all hell".