Kipnuk (Central Yupik: Qipneq) is a census-designated place (CDP) in Bethel Census Area, Alaska, United States.

Kipnuk consists mostly of Yup'ik speaking Native Alaskans; the name means a "bend" referring to the bend in the (Qukaqliq) Kugkaktlik River where it is situated.

The original settlement was situated along "Nukallpiarcunarli", a slough feeding into the (Qukaqliq) Kugkaktlik.

The racial makeup of the CDP was 2.02% White, 96.58% Native American, and 1.40% from two or more races.

10.2% of all households were made up of individuals, and 2.9% had someone living alone who was 65 years of age or older.