A British letter of marque captured her in 1803 and she became a Liverpool-based slave ship in the triangular trade in enslaved people.

In 1803 the letter of marque and slaver Kitty captured the French ship Jeune Amèlie as she was returning from the Indian Ocean with a cargo of sugar, indigo, spices, and muslin.

[2][a] Kitty's Amelia entered Lloyd's Register in 1804 with Nuttall, master, and Thomas Clarke, owner.

However, three mutineers managed to reach HMS Saint Lucia and accused Nuttall of having engaged in transgressions relating to the transportation of captives.

Kitty's Amelia's mate, Thomas Forest, sailed her back to Liverpool from St Barts with a cargo of sugar and cotton.

Kitty's Amelia arrived in Barbados, and then sailed to Trinidad, having repulsed an attack by a French privateer.

Her return cargo consisted of ivory, hides, palm oil, cotton, coffee, indigo, and sugar.

Because they were on a legal voyage, they qualified for a British Royal Navy escort by the 16-gun sloop HMS Favorite, under the command of Lieutenant Frederick Hoffman (acting).

Several times during the voyage Hoffman visited the ships under his care and found them orderly and clean, and the captives healthy.

[17] In contrast with Hoffman's assessment of the state of health aboard the slave ships, Crow, in his memoir, recalled that Kitty's Amelia had lost 30 whites and 50 blacks to sickness on the voyage, the whites included her two doctors, who had died shortly after she arrived at Jamaica.

He further noted that many of the other slave ships that had hurried to beat the deadline for the end of the trade in enslaved people had lost twice as many blacks.

[19] Brassey left Jamaica 24 April 1808 and sailed to Liverpool with a cargo of beeswax, palm oil, elephants' teeth, Madeira wine, rum, sugar, and coffee,[2] arriving on 30 June.

[9] Lloyd's List reported that Kitty's Amelia had foundered in early February 1809 off Maldonado, Uruguay.