She produced film documentaries, responsible for direction and camera, and ran Autorentheater Berlin for new theatre projects.

[5] From 1983, Höfels was a member of the Residenztheater in Munich, where she performed as Princess in Calderón's Das Leben ein Traum, directed by Wilfried Minks [de].

Leading roles there included Anna Petrovna in Michael Frayn's Wild Honey, alongside Gert Voss as Platonov.

She played in crime series such as SOKO, the role of Ingrid Schlüter in the RTL Hinter Gittern – Der Frauenknast from 2006 to 2007.

She played in the series Wilsberg, and in 2020 the physician Dr. Susanne Oppermann in Gute Besserung of the ZDF Ein starkes Team.