Kohoutovice (German: Kohoutowitz) is a municipal part and cadastral territory in the west of the center of Brno, Czech Republic.

Originally an independent municipality, it was annexed to Brno in 1919, since November 24, 1990 it has been part of the city district of Brno-Kohoutovice.

The area around Pavlovská street, on the southern edge of the Kohoutovice cadastre, belonged to the territory of the then municipality of Bosonohy until 1979, while a narrow strip of territory to the west, including a piece of forest and a grove, belonged to the then municipality of Žebětín.

The dominant feature of the district is the Kohoutovice reservoir in the shape of an inverted cone, which can be seen from many sides of Brno.

Kohoutovice borders the cadastral territory of Jundrov to the north, Pisárky to the east, Nový Lískovec to the southeast, Bosonohy to the south and Žebětín to the west.