He then went to the United Kingdom in 1945 and attended Brasenose College, Oxford University, where he was awarded a postgraduate degree in Geography and Education.

[1] Botsio was a teacher at the St. Augustine's College and the London City Council Secondary School in the United Kingdom.

[1] Botsio first met Nkrumah in 1945 while in London, who he would eventually help form the Convention People's Party.

He remained an MP until 1966 when the Parliament of Ghana was suspended by the National Liberation Council which had overthrown the CPP government of Kwame Nkrumah.

[4] He was also at various times, minister for Foreign Affairs, Social Welfare, Transport and Communications, Agriculture, Trade and Development.