Dimitriou began playing football at the age of 4 in the youth academy of Giannitsa, and moved to PAOK in 2013.

[2] On 11 May 2018, Swiss club Basel announced that they had signed Dimitriou from the youth department of PAOK.

To the start of their 2019–20 season under head coach Marcel Koller Dimitriu advanced to Basel's first team.

[4] Two weeks later he played in the Swiss Cup away match against amateur club Pully Football.

[7] Between the years 2018 and 2021 Dimitriou played a total of 12 games for Basel's first team without scoring a goal.