In his professional capacity he was commissioned to redesign and reorganize two historic libraries of the Christian world: those of the Monastery of St John on Patmos (founded in 1089), completed in 1989, and of the Ecumenical Patriarchate in the Phanar, Constantinople (dating from 353, soon after the city's official inauguration as the capital of the Eastern Roman Empire), completed in 1993.
Towards the end of the 1980s Staikos embarked on a systematic study of the history of libraries in the countries of the Mediterranean Basin and the Near East, from earliest antiquity to the Renaissance (about 3000 BC to AD 1600).
"[6] "Libraries were, Staikos reminds us, enmeshed in and thoroughly integrated into Roman life—at least at the top—in ways impossible in later ages.
[7] The Konstantinos Staikos' book collection was acquired by the Onassis Foundation in 2010 as perpetual property of the Greek Nation.
The Konstantinos Staikos' book collection was renamed "Hellenic Library of the Onassis Foundation" and is housed in the neoclassical building at 56 Amalias Avenue Plaka, Athens, Greece.