Born in Athens, Antoniou started his career at Panathinaikos during the late 1970s.
He accepted, but the Panathinaikos president launched legal action and won an appeal for Antoniou to return.
In the winter of 1994 he moved to Athinaikos, where he ended his playing career.
In May 2008, Antoniou returned to his favorite club, this time as a Director of Football.
Antoniou made 35 appearances and scored 3 goals for the Greece national football team from 1984 to 1993.