His writing style often incorporates elements of science fiction with various scientific and philosophical themes, and makes heavy use of plot twists.

A large fan presence helped revive the Zero Escape series, and Uchikoshi returned to write and direct the concluding installment, Zero Time Dilemma (2016).

[1][2] Almost immediately after birth, he began choking on amniotic fluid, and claims he would have died had his doctor not held him upside down and "hit his backside".

Uchikoshi then enrolled in the vocational school Vantan Design Institute, where he studied video game planning, 3D modelling, 2D art, sound, and programming.

[4][6] While writing Never 7: The End of Infinity, Uchikoshi wanted to include science fiction themes, but was instructed by his superiors to instead focus on the romantic relationships between the game's characters.

[4] While working as a freelance writer, Uchikoshi was contacted by the game development company Chunsoft about a possible job offering.

[5] He began implementing and expanding upon these ideas in Nine Hours, Nine Persons, Nine Doors (2009), in which he served as the game director, planner, and scenario writer.

[4] Although the game was a commercial failure in Japan,[9] its unexpected critical success in North America prompted Uchikoshi to continue the series.

[9] Uchikoshi examined the possibility of financing the development through the use of crowdfunding on a website like Kickstarter, but felt that the idea was "not quite persuasive enough".

He wrote a scenario for Steins;Gate: Linear Bounded Phenogram (2013)[4] before working on his first non-game related project, the anime series Punch Line (2015).

[15][16] Uchikoshi also wrote a Punch Line manga, which began serialization in September,[17] and a video game adaptation, released in 2016.

[18] Meanwhile, fans of the Zero Escape series created an online campaign to raise awareness and support the development of a sequel to Virtue's Last Reward.

[11] While delivering the pitch for the game, he used a fan-made vocal rendition of the series theme song; Spike Chunsoft[b] agreed to the proposal, and green-lit production of Zero Time Dilemma (2016).

[4] This style of writing can be seen in Nine Hours, Nine Persons, Nine Doors, as a vital plot point hinged on a Japanese pun, which forced the localization team to play through the entire game again to determine if the story still made sense in English.

[7] Uchikoshi's works often deal with scientific and philosophical themes, including idealism, Rupert Sheldrake's theory of morphic resonance, and the prisoner's dilemma.